Functional Foods Business
Only One Material for People's Health
In order to manufacture safe and high quality products based on our cultivation technology cultivated for over 50 years, we manufacture our products in a hygienic environment and management methods in accordance with Good Manufacturing Practice (GMP) for dietary supplements, including a series of manufacturing processes and quality inspections, to ensure the safety of our products. We strive to ensure that our products are safe and effective. We are committed to providing reliable quality for your valuable products.
Functional Foods Business
Only One Material for People's Health
In order to manufacture safe and high quality products based on our cultivation technology cultivated for over 50 years, we manufacture our products in a hygienic environment and management methods in accordance with Good Manufacturing Practice (GMP) for dietary supplements, including a series of manufacturing processes and quality inspections, to ensure the safety of our products. We strive to ensure that our products are safe and effective. We are committed to providing reliable quality for your valuable products.
The nutritional components of Ganoderma lucidum are completely different from those of Extracts from Ganoderma lucidum mycelium culture medium containing special ingredients [MAK].
Developed in 1996, MAK is a premium product extracted from Ganoderma lucidum, commonly known as Reishi or Mannentake, which has been highly valued in traditional Chinese medicine since ancient times. This innovative product is created through a specialized process that cultivates Reishi mushroom mycelium extracts.
MAK stands out due to its unique and beneficial compounds produced by the Ganoderma lucidum mycelium as it metabolizes and grows on nutrient-rich substrates such as bagasse and rice bran. These natural substances are believed to contribute to immune support and overall health enhancement.
By incorporating MAK into your "mycelium lifestyle," you can improve your health and vitality, making it an excellent choice for those seeking natural health solutions.
The nutritional components of Ganoderma lucidum are completely different from those of Extracts from Ganoderma lucidum mycelium culture medium containing special ingredients [MAK].
Developed in 1996, MAK is a premium product extracted from Ganoderma lucidum, commonly known as Reishi or Mannentake, which has been highly valued in traditional Chinese medicine since ancient times. This innovative product is created through a specialized process that cultivates Reishi mushroom mycelium
extracts.
MAK stands out due to its unique and beneficial compounds produced by the Ganoderma lucidum mycelium as it metabolizes and grows on nutrient-rich substrates such as bagasse and rice bran. These natural substances are believed to contribute to immune support and overall health enhancement.
By incorporating MAK into your "mycelium lifestyle," you can improve your health and vitality, making it an excellent choice for those seeking natural health solutions.
The Bioactive Components of MAK and Their Effects
MAK is rich in various bioactive compounds that contribute to health. Notably, it contains two primary components: heteropolysaccharides and water-soluble lignin. These compounds are produced by enzymes within the mycelium of **Astragalus membranaceus**, which also generates unique enzymes not found in shiitake mushroom mycelium.
Composition and Characteristics of Heteropolysaccharides
Heteropolysaccharides are primarily composed of pentasaccharides such as arabinose and xylose, as well as hexoses like glucose. These components play a significant role in various physiological functions within the body, particularly in enhancing immune function and providing antioxidant effects.
Diverse Health Benefits of MAK
MAK offers a wide range of health benefits, including:
1. **Antioxidant Effects**: Reduces oxidative stress in cells, contributing to the prevention of aging and diseases.
2. **Neuroprotective Effects**: Protects nerve cells and supports brain health.
3. **Blood Sugar Regulation**: Helps prevent rapid spikes in blood sugar levels, aiding in diabetes prevention.
4. **Blood Pressure Regulation**: Reduces the risk of hypertension and promotes cardiovascular health.
5. **Immune Modulation**: Adjusts immune system responses, enhancing resistance to infections.
6. **Antiviral Properties**: Strengthens the body’s defenses against viral infections.
7. **Mood Improvement**: Supports mental health and contributes to the reduction of stress and anxiety.
Conclusion
MAK, with its rich array of bioactive components, provides numerous health benefits. Its ability to enhance immune function and offer antioxidant protection is particularly important in today’s health-conscious society. By incorporating MAK into your daily routine, you can support health maintenance and disease prevention. Consider utilizing MAK as part of a health-focused lifestyle to reap its potential benefits.
Changes in Sugar Composition Due to Cultivation Process
| Sugar Composition of Culture Medium | Sugar Composition of Mycelium | Sugar Composition of MAK | ||
| Hexose | Glucose | 62 | 50 | 40 |
| Galactose | 17 | 16 | 8 | |
| Mannose | 3 | 12 | 2 | |
| Rhamnose | 0 | 0 | 5 | |
| Fucose | 0 | 3 | 1 | |
| Pentose | Arabinose | 13 | 3 | 15 |
| Xylose | 5 | 14 | 29 |
Changes in Sugar Composition Due to Cultivation Process
| Sugar Composition of Culture Medium | Sugar Composition of Mycelium | Sugar Composition of MAK | ||
| Hexose | Glucose | 62 | 52 | 40 |
| Galactose | 17 | 16 | 8 | |
| Mannose | 3 | 12 | 2 | |
| Pentose | Arabinose | 13 | 3 | 15 |
| Xylose | 5 | 14 | 29 | |
| Hexose | Rhamnose | 0 | 0 | 0 |
| Fucose | 0 | 3 | 0 |
Safety of MAK
The mycelium used in the production of MAK is the same as that of the edible mannentake mushroom. Therefore, there are no safety issues. The safety of MAK has been confirmed through various safety tests, including toxicity and mutagenicity tests, conducted by an analytical laboratory.
| Acute toxicity | rat | Threshold dose study No abnormality |
NLT 22,500mg/kg |
| mouse | 2,000mg/kg | ||
| Mutagenicity | Negative | ||
| Repeated-dose study (three months) |
rat (male) | NOAEL | 3,610mg/kg/day |
| rat (fermale) | NOAEL | 4,190mg/kg/day | |
Safety of MAK
The mycelium used in the production of MAK is the same as that of the edible mannentake mushroom. Therefore, there are no safety issues. The safety of MAK has been confirmed through various safety tests, including toxicity and mutagenicity tests, conducted by an analytical laboratory.
| Acute toxicity | rat | Threshold dose study No abnormality |
NLT 22,500mg/kg |
| mouse | 2,000mg/kg | ||
| Mutagenicity | Negative | ||
| Repeated-dose study (three months) |
rat (male) | NOAEL | 3,610mg/kg/day |
| rat (fermale) | NOAEL | 4,190mg/kg/day | |
Examples of MAK Effectiveness Tests
▒ Antioxidant action
The 50% inhibitory concentration (ICso) was calculated for two antioxidant activities of MAK: O2 (superoxide anion) scavenging capacity and inhibition of lipid peroxide production. The results showed that MAK had antioxidant capacity comparable to that of vitamin C and vitamin E.
Examples of MAK Effectiveness Tests
▒ Antioxidant action
The 50% inhibitory concentration (ICso) was calculated for two antioxidant activities of MAK: O2 (superoxide anion) scavenging capacity and inhibition of lipid peroxide production. The results showed that MAK had antioxidant capacity comparable to that of vitamin C and vitamin E.
▒ Brain cell protective effects
Type I diabetic mice were divided into three groups: one group received MAK (0.3 or 1 g/kg) dissolved in distilled water orally and the other group received distilled water only. Administration was done once a day for 7 days. Half of the brains were then treated with hypoxia and observed for brain cell protection. The results showed that the formation of cerebral infarcts was inhibited in the MAK-treated group. In particular, the inhibitory effect was particularly high in the 1 g/kg dose group.
▒ Brain cell protective effects
Type I diabetic mice were divided into three groups: one group received MAK (0.3 or 1 g/kg) dissolved in distilled water orally and the other group received distilled water only. Administration was done once a day for 7 days. Half of the brains were then treated with hypoxia and observed for brain cell protection. The results showed that the formation of cerebral infarcts was inhibited in the MAK-treated group. In particular, the inhibitory effect was particularly high in the 1 g/kg dose group.
We can also provide you with samples of each raw material.
We can also provide you with samples of each raw material.